منابع مشابه
Localization of oskar RNA regulates oskar translation and requires Oskar protein.
The site of oskar RNA and protein localization within the oocyte determines where in the embryo primordial germ cells form and where the abdomen develops. Initiation of oskar RNA localization requires the activity of several genes. We show that ovaries mutant for any of these genes lack Oskar protein. Using various transgenic constructs we have determined that sequences required for oskar RNA l...
متن کاملKarl Oskar Illmensee (1939?)
Karl Oskar Illmensee studied the cloning [2] and reproduction of fruit flies, mice, and humans [3] in the US and Europe during the twentieth and twenty-first centuries. Illmensee used nuclear transfer techniques (cloning [2]) to create early mouse [4] embryos from adult mouse [4] cells, a technique biologists used in later decades to help explain how embryonic cells function during development....
متن کاملOskar Fischer and the study of dementia
The centenary of Alois Alzheimer's description of the case of Auguste Deter has renewed interest in the early history of dementia research. In his 1907 paper Alzheimer described the presence of plaques and tangles in one case of presenile dementia. In the same year, Oskar Fischer reported neuritic plaques in 12 cases of senile dementia. These were landmark findings in the history of research in...
متن کاملStructure of Drosophila Oskar reveals a novel RNA binding protein.
Oskar (Osk) protein plays critical roles during Drosophila germ cell development, yet its functions in germ-line formation and body patterning remain poorly understood. This situation contrasts sharply with the vast knowledge about the function and mechanism of osk mRNA localization. Osk is predicted to have an N-terminal LOTUS domain (Osk-N), which has been suggested to bind RNA, and a C-termi...
متن کاملEvolution: oskar Reveals Missing Link in Co-optive Evolution
The oskar gene is critical for germ plasm formation and reproduction in higher insects. A recent study reports that oskar has more ancient roots than previously thought, indicating it was co-opted for its reproductive role in higher insects.
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ژورنال
عنوان ژورنال: DMW - Deutsche Medizinische Wochenschrift
سال: 1907
ISSN: 0012-0472,1439-4413
DOI: 10.1055/s-0029-1202974